Sunifiram is a powerful AMPAkine(targets mainly AMPA(and possibly NMDA to a degree) receptors, 2 of 3 main subsets of glutamate receptors) and is a synthetically altered semi-derivative of the proto-noot, Piracetam.
Despite being a newer compound and having limited human research, preliminary reports have shown Sunifiram to postively effect LTP(long-term potentiation) levels in the hippocampus, which increases synaptic plasticity, long term, meaning it tunes synapses’ individual wavelengths to their neighbors when used, enhancing their signal transmission and pathways, leading to increased memory retention and perceptual sensory data absorption. It also aids in the release of acetylcholine in the prefrontal cortex up to 200%, and has been shown to increase sensitivity to stims(including caffeine and finils), making stacking them oftentimes unnecessary and undesirable.
Effects may include:
*Enhanced absorption of sensory data(vision, sound, taste, etc)
*Increased dream quality/realism
*Increased memory consolidation/recall
*A feeling of calm, focused energy
*Potentiation; An increased sensitivity to noots/stims/psychedelics
It may be taken in caps, or may be dissolved in liquid with little degradation and taste-masking.
Unifiram is a newer compound very similar in structure to Sunifiram, but the synthesizing process is much more difficult and costly. Differences include a slightly smaller necessary dosage, and in-vitro studies have shown it to increase the amplitude of fEPSP(field excitatory postsynaptic potential) in the hippocampus of mice, meaning it essentially increases the overall power output in the brains neural field, strengthening the signals and increasing their firing speed farther than Suni’s LTP-tuning effects.
An essential nutrient, Choline is the precursor to a neurotransmitter heavily involved in memory and nerve communication(Acetylcholine). It can be found naturally in fattier proteins such as poultry, eggs, milk and almonds. It has an especially synergistic reaction with racetams, fueling their effects.
Choline supplements are often taken as a form of ‘smart drug’ or nootropic due to the role the neurotransmitter acetylcholine plays in various cognition systems within the brain. Choline is a chemical precursor or “building block” needed to produce acetylcholine, and research suggests that memory, intelligence, and mood are mediated at least in part by acetylcholine metabolism in the brain.
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